Fungal Infections

There are several antifungal agents available. Many are off patent with numerous generic formulations. Very large numbers of topical azoles are available clinically for thrush; not all these are covered here. The table below explains the common formulations of the most important preparations in clinical use. Not all antifungals are available in all countries and some data sheets differ.

Many drug interactions are recognised with antifungal drugs. These can be searched here for the most commonly used oral and intravenous antifungals.

Class

Antifungal

Topical

Oral

Intravenous

Polyene

Amphotericin B

X

 

X

 

Nystatin

X

 

 

 

Natamycin

X

 

 

Tubulin disrupter

Griseofulvin

 

X

 

Azoles

Clotrimazole

X

 

 

 

Econazole

X

 

 

 

Ketoconazole

X

X

 

 

Fluconazole

 

X

X

 

Isavuconazole

 

X

X

 

Itraconazole

 

X

X

 

Voriconazole

 

X

X

 

Posaconazole

 

X

X

Allylamine

Terbinafine

X

X

 

Pyrimidine analog

Flucytosine

 

X

X

Echinocandin

Caspofungin

 

 

X

 

Micafungin

 

 

X

 

Anidulafungin

 

 

X

 

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