Fungal Infections

Species/common name:

Rhizopus microsporus. There are 4 varieties var. microsporus, var. rhizopodiformis, var. oligosporus, and var. chinensis

Natural habitat

Most common in soil and decaying plant debris and foodstuffs.

Geography

Worldwide distribution.

Frequency

Frequency is unknown but it is accepted as the second most common cause of mucormycosis. This species is associated with gastrointestinal and cutaneous infections and mycotic abortion in animals.

Diseases

Humans: particularly associated with the cutaneous and gastrointestinal forms of the disease. Outbreaks of intestinal infections have been reported. Other forms of the disease as pulmonary, rhinocerebral, central nervous system and disseminated infections are less frequent caused by this fungus.

Animals: It is the most frequent Mucorales causing infections in other mammals mainly swine and bovine abortion.

Culture peculiarities

Fast growing; hairy, dark greyish-brown. Sporangiophores are brownish and more common in pairs. Sporangia spherical and greyish-black in colour. Sporangiospores hyaline, angular, subspherical or ellipsoidal and striate. It can grow at 50-52ºC. the differentiation between varieties require great expertise or the sequencing of DNA targets.

Antifungal resistance (intrinsic and acquired)

All isolates are intrinsically resistant to fluconazole, ketoconazole, voriconazole and the echinocandins. Usually susceptible to amphotericin B and posaconazole. Variably susceptible to itraconazole.

Biosafety level 2

This organism can be handled in a biosafety level 2 laboratory.

Industrial use:

It is used in the production of tempeh, a natural soy product originally from Indonesia.

Images


Macroscopic morphology of Rhizopus microsporus.

Take action today

Educate

Recognise & treat fungal
infections: See opportunities for
learning.

Participate

See our news section.
Sign up for
the Newsletter.

Spread
the word

Help us change as many
lives as possible by
sharing this site!