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Indonesian army affected by tinea pedis;  PCR for T. marneffei infection…

October 27 2016

Indonesian army affected by tinea pedis;  PCR for T. marneffei infection; Fonsecaea nubica; Malassezia systemic infections in neonates and fungal diseases in the Philippines

At the 6th Asian-Pacific Society for Medical Mycology (APSMM) meeting in Bali, Indonesia, Dr Samodra reported on the high frequency of tinea pedis in soldiers. In a sample of 100, from the 475,000 active personnel (tentara Nasional Indonesia), 46 had tinea pedis. The most common form was interdigital (athlete’s foot) in 26 cases, moccasin type in 12 and vesiculobullous in 6. Bacterial super-infection was found in 2 patients

Also reported was the clearcut utility of PCR to detect Talaromyces (formerly Penicillium) marneffei infection. Dr Coa from Guangxi Medical University found real time PCR out-perfomed galactomannan detection in blood (sensitivity 95% vs 78%: specificity 100% vs 83%) in cases of disseminated and other T. marneffei infections.

In China, cases of chromoblastomycosis are attributable to Fonsecaea monophora and Fonsecaea nubica and no cases have been found attributable to Fonsecaea pedrosoi, according to Drs Peiying and Francisca from Guangzhou.

In premature neonates in Moscow, a prospective study of disseminated Malassezia furfur infections, found conventional blood cultures systems to be unsatisfactory compared with liquid Dixon medium: 0.2% vs 5.3%. In 99 infants <1500g at birth, M. furfur was cultured in 22%, from urine in 15% and blood in 6%. Attention to microbiological detail in neonates is called for.

Syarief Hidayat, Hideoki Ogawa, Retno Wahyuningsih, Kusmarinah Bramono

The burden of serious fungal disease in the Philippines was presented by Dr Batac from Manila. About 1.9% of the 98 million Filipinos are affected, including a few cases of mycetoma but not including histoplasmosis because of a complete lack of data. Estimates of invasive aspergillosis, invasive candidiasis and Pneumocystis pneumonia are uncertain, the last being especially problematic as HIV infections are rising rapidly.

Over 360 physicians and scientists attended the 6th ASPMM meeting which was held in association with the Indonesian Society for Human and Animal Mycology (INSHAM) and The Indonesian Society for Dermatology and Venereology (ISDV). A pre-congress workshop on diagnosis attracted 100 people and was supported by the Medical Mycology Training Network and the Asia Fungal Working Group (AFWG).

Prof Retno Wahyuningsih of the Universitas Kristen Indonesia and Universitas Indonesia, and President of INSHAM said: “The breadth and diversity of cases of cutaneous and systemic fungal diseases presented in 100 posters is extraordinary. Asia has such a rich diversity of human fungal disease, not yet matched by our diagnostic capability. I am particularly concerned that we are missing many cases of histoplasmosis, chronic aspergillosis and cryptococcosis. Talaromyces is rarely diagnosed presently in most places and elsewhere there may more hidden cases waiting to be diagnosed.“  

Phillipines Burden of Disease Poster