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Length of stay in intensive care linked to risk of resistant Candida infections

June 29 2015

The China-SCAN team have released a study surveying fluconazole resistance in invasive Candida infections (ICIs) affecting intensive care unit (ICU) patients across China.

In total 219 patients were surveyed, with 90 (41%) being resistant to fluconazole. The most commonly resistant species was C.parapsilosis (n = 27), followed by C. glabrata (n = 26). Mixed infections were almost invariably resistant to fluconazole (83% of mixed infections resistant). Patients with resistant ICIs were in hospital or ICU longer before the onset of infection than the sensitive group, with length of stay in ICU being a risk factor for fluconazole resistant Candida infections.

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