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The clinical features and epidemiology of oral paracoccidioidomycosis

June 12 2017

A recent study has presented an analysis of the clinical and epidemiological characteristics of Brazilian patients with oral paracoccidioidomycosis (PCM)- a deep mycosis endemic to Latin America. In this study Aline Trindade and colleagues from the Federal University of Minas Gerais School of Dentistry in South Eastern Brazil collected data retrospectively from 1998 to 2015 of 55 histopathologically confirmed cases of oral PCM diagnosed at their Maxillofacial Pathology Laboratory

Oral lesions were usually painful (reported by 61.82% of patients) and erythematous (seen in 73% of patients). If there was a single lesion (42%), it most commonly affected the tongue or jugal (cheek) mucosa and multiple lesions (58%) commonly affected the lips, jugal mucosa and alveolar ridge. Oral PCM lesions are classically irregular, “mulberry-like” (due to bleeding petechiae), ulcerated and granulomatous. They are a common clinical feature of this important and potentially fatal mycosis.

The key epidemiological findings, which roughly corroborate those of similar studies, were that 90.9% of patients were male and though the ages of patients ranged from 6-81, the average age at diagnosis was 50 years. The majority of patients for which employment data was collected were agricultural or construction workers.